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근래에 국제 학술지 '자마 피부과학(JAMA Dermatology)'에 피나스테리드를 복용하는 45세 이하 여성은 위험한 선택 및 우울감 위험이 높다는 테스트 결과가 나왔다. 미국 브리검 남성병원 공부진은 세계보건기구(WHO)가 수집한 부작용 사례를 분석했다.
만성 스트레스가 모낭(hair follicle) 줄기세포의 재생 기능을 방해하는 생물학적 메커니즘을 미국 하버드대 실험진이 보였다. 스트레스를 받을 때 분비되는 호르몬이, 모낭 줄기세포의 휴지기(rest phase)를 연장해 재생을 장기간 멈추게 하는 것으로 보여졌다.
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